Jichu yixue yu linchuang (Aug 2021)

Research progress of HIF-1 mediated autophagy in cardiac diseases

  • ZHANG Liu-jie, LI Jing, WU Bo

Journal volume & issue
Vol. 41, no. 8
pp. 1186 – 1189

Abstract

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Hypoxia-inducible factor 1 (HIF-1) regulates the expression of target genes to keep the balance between oxygen supply and oxygen consumption, maintains oxygen homeostasis. HIF-1 regulates autophagy in the cardiovascular system, which involves the HIF target gene BNIP3.

Keywords