Journal of Pharmacy and Bioallied Sciences (Jan 2021)

Cariostatic efficacy of cinnamon water extract on Streptococcus mutans: An In vitro study

  • Nutan Mala,
  • Sinha Sonal,
  • Amit Kumar,
  • Harsh Vardhan Choudhary,
  • Prafulla Songara,
  • Kumar Ramesh

DOI
https://doi.org/10.4103/jpbs.jpbs_677_20
Journal volume & issue
Vol. 13, no. 5
pp. 212 – 216

Abstract

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Background: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. Objectives: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. Materials and Methods: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. Results: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). Conclusion: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract.

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