1,4-Naphthoquinone Is a Potent Inhibitor of IRAK1 Kinases and the Production of Inflammatory Cytokines in THP‑1 Differentiated Macrophages

• Ismail Sami Mahmoud,
• Ma’mon M. Hatmal,
• Duaa Abuarqoub,
• Ezaldeen Esawi,
• Hiba Zalloum,
• Suha Wehaibi,
• Hamdi Nsairat,
• Walhan Alshaer

Affiliations

Ismail Sami Mahmoud

Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan

Ma’mon M. Hatmal

Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, The Hashemite University, Zarqa, Jordan

Duaa Abuarqoub

Cell Therapy Centre, The University of Jordan, Amman, Jordan

Ezaldeen Esawi

Cell Therapy Centre, The University of Jordan, Amman, Jordan

Hiba Zalloum

Hamdi Mango Centre for Scientific Research, The University of Jordan, Amman, Jordan

Suha Wehaibi

Cell Therapy Centre, The University of Jordan, Amman, Jordan

Hamdi Nsairat

Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan

Walhan Alshaer

Cell Therapy Centre, The University of Jordan, Amman, Jordan