Salvage LATTICE radiotherapy for a growing tumour despite conventional radio chemotherapy treatment of lung cancer

Rémy Kinj; Alessio Casutt; Tu Nguyen-Ngoc; Ange Mampuya; Luis Schiappacasse; Jean Bourhis; Constance Huck; David Patin; Maud Marguet; Michele Zeverino; Raphaël Moeckli; Michel Gonzalez; Alban Lovis; Mahmut Ozsahin

Clinical and Translational Radiation Oncology (Mar 2023)

Salvage LATTICE radiotherapy for a growing tumour despite conventional radio chemotherapy treatment of lung cancer

Rémy Kinj,
Alessio Casutt,
Tu Nguyen-Ngoc,
Ange Mampuya,
Luis Schiappacasse,
Jean Bourhis,
Constance Huck,
David Patin,
Maud Marguet,
Michele Zeverino,
Raphaël Moeckli,
Michel Gonzalez,
Alban Lovis,
Mahmut Ozsahin

Affiliations

Rémy Kinj: Department of Radiation Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland; Corresponding author at: Department of Radiation Oncology, CHUV, Rue du Bugnon 46, Lausanne CH-1011, Switzerland.
Alessio Casutt: Department of Pulmonology, Lausanne University Hospital (CHUV) and Lausanne University (UNIL), Lausanne, Switzerland
Tu Nguyen-Ngoc: Department of Medical Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Ange Mampuya: Department of Radiation Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Luis Schiappacasse: Department of Radiation Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Jean Bourhis: Department of Radiation Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Constance Huck: Department of Radiation Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
David Patin: Institute of Radiation Physics, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Maud Marguet: Institute of Radiation Physics, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Michele Zeverino: Institute of Radiation Physics, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Raphaël Moeckli: Institute of Radiation Physics, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
Michel Gonzalez: Department of Thoracic Surgery, University Hospital Center of Lausanne (CHUV), and University of Lausanne (UNIL), Lausanne, Switzerland
Alban Lovis: Department of Pulmonology, Lausanne University Hospital (CHUV) and Lausanne University (UNIL), Lausanne, Switzerland
Mahmut Ozsahin: Department of Radiation Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland

Journal volume & issue: Vol. 39
p. 100557

Abstract

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A 40-year-old patient with cT4cN1M0 squamous cell lung cancer of the upper right lobe received preoperative induction chemotherapy. Systemic induction treatment failed to reverse tumour growth with the addition of conventional radiotherapy (RT). A salvage lattice RT boost of 12 Gy was administered immediately to increase the dose to the tumour. Conventional RT was resumed at the planned dose of 60 Gy. The tumour shrank rapidly, and the patient was surged. The postoperative pathology remained ypT0ypN0 status.

Published in Clinical and Translational Radiation Oncology

ISSN: 2405-6308 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.journals.elsevier.com/clinical-and-translational-radiation-oncology

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