Advances in prevention and control for dengue fever

Abstract

Dengue fever is an acute infectious disease caused by mosquito vector bites carrying dengue virus. Dengue fever has been prevalent in more than 100 countries and regions, with about 390 million people infected each year. In early 2019, the World Health Organization (WHO) listed dengue fever caused by dengue virus as one of the top 10 threats to global health in 2019. From the beginning of 2019 to the end of August, dengue fever outbreaks have occurred in more than 20 countries and regions around the world, with more than 1.5 million cases of infection. Up to date, it is not clear about the pathogenesis of dengue fever, and there is no target drug. Vaccine prevention and mosquito vector control are effective means to control the transmission of the virus. Vaccine prevention and mosquito vector control are effective means to curb the spread of dengue virus. This article reviews the latest progress in the research and development of dengue vaccine and mosquito vector control in recent years. The development of dengue vaccine in the future is expected to make breakthroughs in the reassembly of dominant antigens and the development of new delivery systems. The rise of new technologies such as gene editing will promote the development of mosquito vector control research.

Keywords

• dengue fever
• dengue virus
• mosquito vector
• vaccine
• prevention and control