SURGICAL TREATMENT OF PRIMARY MACULAR HOLE USING PLATELET-RICH PLASMA

Abstract

Purpose. To assess the efficacy of surgical treatment of primary macular hole (MH) using platelet-rich plasma (PRP). Material and methods. In the study there were examined and operated 39 individuals with primary MH. During the surgery, after internal limiting membrane (ILM) removal the application of platelet-rich plasma was performed on the region of the hole without mechanical edge closing. The fibrin PRP component provides a «binding» of the hole edges and prevents wicking of fluid. The preoperative visual acuity was from 0.02 to 0.4 (0.16±0.1). Results. In the postoperative follow-up period the anatomical closure was confirmed in all cases as well as an improvement of visual functions was achieved. No intra- and post-operative complications were noted in any case. In the follow-up period up to 3 months a far vision improvement (in patients with a small MH up to 0.6±0.2, with a moderate MH up to 0.5±0.2, with a large МH up to 0.5±0.2) and in the near vision (0.6±0.2, 0.6±0.2 and 0.5±0.2, respectively). Conclusion. This new technique of primary macular hole treatment is associated with better anatomical and functional results.

Keywords

• primary macular hole
• platelet-rich plasma
• internal limiting membrane
• vitrectomy
• vitreomacular interface