Added Value of Cone-Beam Computed Tomography for Detecting Hepatocellular Carcinomas and Feeding Arteries during Transcatheter Arterial Chemoembolization Focusing on Radiation Exposure
Duk-Ju Kim,
In Chul-Nam,
Sung-Eun Park,
Doo-Ri Kim,
Jeong-Sub Lee,
Bong-Soo Kim,
Guk-Myung Choi,
JeongJae Kim,
Jung-Ho Won
Affiliations
Duk-Ju Kim
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
In Chul-Nam
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
Sung-Eun Park
Department of Radiology, Gyeongsang National University, School of Medicine, Gyeongsang National University Changwon Hospital, 11 Samjeongja-ro, Seongsan-gu, Changwon 51472, Republic of Korea
Doo-Ri Kim
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
Jeong-Sub Lee
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
Bong-Soo Kim
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
Guk-Myung Choi
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
JeongJae Kim
Department of Radiology, Jeju National University, School of Medicine, Jeju Natuional University Hospital, 15, Aran 13-gil, Jeju 63241, Republic of Korea
Jung-Ho Won
Department of Radiology, Gyeongsang National University, School of Medicine, Gyeongsang National University Hospital, Jinju 52727, Republic of Korea
Background and Objectives: This study aimed to evaluate the added value of cone-beam computed tomography (CBCT) for detecting hepatocellular carcinomas (HCC) and feeding arteries during transcatheter arterial chemoembolization (TACE). Material and methods: Seventy-six patients underwent TACE and CBCT. We subcategorized patients into groups I (61 patients: possible superselection of tumor/feeding arteries) and II (15 patients: limited superselection of tumor/feeding arteries). We evaluated fluoroscopy time and radiation dose during TACE. Two blinded radiologists independently performed an interval reading based on digital subtraction angiography (DSA) imaging only and DSA combined with CBCT in group I. Result: The mean total fluoroscopy time was 1456.3 ± 605.6 s. The mean dose–area product (DAP), mean DAP of CBCT, and mean ratio of DAP of CBCT to total DAP was 137.1 ± 69.2 Gy cm2, 18.3 ± 7.1 Gy cm2, and 13.3%, respectively. The sensitivity for detecting HCC increased after the additional CBCT reading, from 69.6% to 97.3% and 69.6% to 96.4% for readers 1 and 2, respectively. The sensitivity for detecting feeding arteries increased from 60.3% to 96.6% and 63.8% to 97.4% for readers 1 and 2, respectively. Conclusions: CBCT can increase sensitivity for detecting HCCs and feeding arteries without significantly increasing the radiation exposure.
