Nature Communications (Jun 2020)

Direct transfer of tri- and di-fluoroethanol units enabled by radical activation of organosilicon reagents

  • Xiang Chen,
  • Xingxing Gong,
  • Zhengyu Li,
  • Gang Zhou,
  • Zhihong Zhu,
  • Weilu Zhang,
  • Shanshan Liu,
  • Xiao Shen

DOI
https://doi.org/10.1038/s41467-020-16380-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

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Methods for direct incorporation of tri- and di-fluoroethanol units in molecules are relatively limited. Here, the authors report two organosilicon reagents which are applied to allylation, alkylation and alkenylation reactions as tri- and di-fluoroethanol transfer reagents.