Photocatalytic direct borylation of carboxylic acids

Qiang Wei; Yuhsuan Lee; Weiqiu Liang; Xiaolei Chen; Bo-shuai Mu; Xi-Yang Cui; Wangsuo Wu; Shuming Bai; Zhibo Liu

doi:10.1038/s41467-022-34833-1

Nature Communications (Nov 2022)

Photocatalytic direct borylation of carboxylic acids

Qiang Wei,
Yuhsuan Lee,
Weiqiu Liang,
Xiaolei Chen,
Bo-shuai Mu,
Xi-Yang Cui,
Wangsuo Wu,
Shuming Bai,
Zhibo Liu

Affiliations

Qiang Wei: Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University
Yuhsuan Lee: Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences
Weiqiu Liang: Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University
Xiaolei Chen: Radiochemistry Laboratory, School of Nuclear Science and Technology, Lanzhou University
Bo-shuai Mu: Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University
Xi-Yang Cui: Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University
Wangsuo Wu: Radiochemistry Laboratory, School of Nuclear Science and Technology, Lanzhou University
Shuming Bai: Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences
Zhibo Liu: Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University

DOI: https://doi.org/10.1038/s41467-022-34833-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 9

Abstract

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Boronic acids are useful reagents in organic synthesis and thus methods to prepare these compounds under mild conditions are desirable. Here, the authors synthesize boronic acids via photocatalytic decarboxylation of benzoic acids followed by borylation; guanidine-type additives are used to assist the process.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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