Communications Medicine (Oct 2021)
Host methylation predicts SARS-CoV-2 infection and clinical outcome
- Iain R. Konigsberg,
- Bret Barnes,
- Monica Campbell,
- Elizabeth Davidson,
- Yingfei Zhen,
- Olivia Pallisard,
- Meher Preethi Boorgula,
- Corey Cox,
- Debmalya Nandy,
- Souvik Seal,
- Kristy Crooks,
- Evan Sticca,
- Genelle F. Harrison,
- Andrew Hopkinson,
- Alexis Vest,
- Cosby G. Arnold,
- Michael G. Kahn,
- David P. Kao,
- Brett R. Peterson,
- Stephen J. Wicks,
- Debashis Ghosh,
- Steve Horvath,
- Wanding Zhou,
- Rasika A. Mathias,
- Paul J. Norman,
- Rishi Porecha,
- Ivana V. Yang,
- Christopher R. Gignoux,
- Andrew A. Monte,
- Alem Taye,
- Kathleen C. Barnes
Affiliations
- Iain R. Konigsberg
- School of Medicine, University of Colorado Anschutz Medical Campus
- Bret Barnes
- Illumina, Inc.
- Monica Campbell
- School of Medicine, University of Colorado Anschutz Medical Campus
- Elizabeth Davidson
- School of Medicine, University of Colorado Anschutz Medical Campus
- Yingfei Zhen
- School of Medicine, University of Colorado Anschutz Medical Campus
- Olivia Pallisard
- School of Medicine, University of Colorado Anschutz Medical Campus
- Meher Preethi Boorgula
- School of Medicine, University of Colorado Anschutz Medical Campus
- Corey Cox
- School of Medicine, University of Colorado Anschutz Medical Campus
- Debmalya Nandy
- Colorado School of Public Health, University of Colorado Anschutz Medical Campus
- Souvik Seal
- Colorado School of Public Health, University of Colorado Anschutz Medical Campus
- Kristy Crooks
- School of Medicine, University of Colorado Anschutz Medical Campus
- Evan Sticca
- School of Medicine, University of Colorado Anschutz Medical Campus
- Genelle F. Harrison
- School of Medicine, University of Colorado Anschutz Medical Campus
- Andrew Hopkinson
- School of Medicine, University of Colorado Anschutz Medical Campus
- Alexis Vest
- School of Medicine, University of Colorado Anschutz Medical Campus
- Cosby G. Arnold
- School of Medicine, University of Colorado Anschutz Medical Campus
- Michael G. Kahn
- School of Medicine, University of Colorado Anschutz Medical Campus
- David P. Kao
- School of Medicine, University of Colorado Anschutz Medical Campus
- Brett R. Peterson
- School of Medicine, University of Colorado Anschutz Medical Campus
- Stephen J. Wicks
- School of Medicine, University of Colorado Anschutz Medical Campus
- Debashis Ghosh
- Colorado School of Public Health, University of Colorado Anschutz Medical Campus
- Steve Horvath
- University of California Los Angeles
- Wanding Zhou
- The Children’s Hospital of Philadelphia
- Rasika A. Mathias
- School of Medicine, University of Colorado Anschutz Medical Campus
- Paul J. Norman
- School of Medicine, University of Colorado Anschutz Medical Campus
- Rishi Porecha
- Illumina, Inc.
- Ivana V. Yang
- School of Medicine, University of Colorado Anschutz Medical Campus
- Christopher R. Gignoux
- School of Medicine, University of Colorado Anschutz Medical Campus
- Andrew A. Monte
- School of Medicine, University of Colorado Anschutz Medical Campus
- Alem Taye
- Illumina, Inc.
- Kathleen C. Barnes
- School of Medicine, University of Colorado Anschutz Medical Campus
- DOI
- https://doi.org/10.1038/s43856-021-00042-y
- Journal volume & issue
-
Vol. 1,
no. 1
pp. 1 – 10
Abstract
Konigsberg et al. profile DNA methylation in blood samples from SARS-CoV-2 cases and controls. The authors use machine learning to classify infected vs. non-infected individuals and predict clinical outcomes related to disease severity.
