Genes and Diseases (Mar 2024)
The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer
- Jiyan Wang,
- Tao He,
- Qingle Gao,
- Hongkai Chang,
- Xintong Dai,
- Juze Yang,
- Shuangping Liu,
- Shuai Zhang,
- Changliang Shan,
- Chunze Zhang
Affiliations
- Jiyan Wang
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China
- Tao He
- Departments of Pathology, Characteristic Medical Center of The Chinese People's Armed Police Force, Tianjin 300162, China
- Qingle Gao
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China
- Hongkai Chang
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China
- Xintong Dai
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China
- Juze Yang
- Department of Respiratory Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, China
- Shuangping Liu
- Department of Pathology, Medical School, Dalian University, Dalian, Liaoning 116622, China
- Shuai Zhang
- School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
- Changliang Shan
- State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300350, China; Corresponding author.
- Chunze Zhang
- Department of Colorectal Surgery, Tianjin Union Medical Center, Nankai University, Tianjin 300121, China; Corresponding author.
- Journal volume & issue
-
Vol. 11,
no. 2
pp. 542 – 545