Light: Science & Applications (Jan 2021)

Toward optical coherence tomography on a chip: in vivo three-dimensional human retinal imaging using photonic integrated circuit-based arrayed waveguide gratings

  • Elisabet A. Rank,
  • Ryan Sentosa,
  • Danielle J. Harper,
  • Matthias Salas,
  • Anna Gaugutz,
  • Dana Seyringer,
  • Stefan Nevlacsil,
  • Alejandro Maese-Novo,
  • Moritz Eggeling,
  • Paul Muellner,
  • Rainer Hainberger,
  • Martin Sagmeister,
  • Jochen Kraft,
  • Rainer A. Leitgeb,
  • Wolfgang Drexler

DOI
https://doi.org/10.1038/s41377-020-00450-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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Optical coherence tomography: chip promise The goal of an optical coherence tomography (OCT) imaging system that is integrated on a photonic chip has taken a step closer to reality. Elisabet Rank and coworkers from Austria have shown that arrayed waveguide gratings (AWGs), integrated-optical devices commonly used to separate different wavelength channels in an optical communications system, can be used to replace diffraction gratings in an OCT system. Several designs of silicon nitride AWGs with 256 channels in the near-infrared were fabricated and then tested in an OCT system which was able to capture in-vivo tomograms and angiography of the human eye’s retina, with comparable quality to a conventional system. The next stage of the OCT-on-a-chip research will focus on exploring the use of multimode interference structures, integrated photodiodes, and compact light sources.