Hormones of Adipose Tissue and Gestational Diabetes

Abstract

Obesity and gestational diabetes are the risk factors for complications both in the mother and in the fetus. Adipose tissue hormones (leptin, adiponectin, resistin) are secreted by the human placenta and regulate the function of trophoblast. The review presents data from the literature on the role of adipocytokines in the development of gestational diabetes and preeclampsia in obese women. The article considers the criteria and algorithms for the diagnosis of gestational diabetes recommended by the World Health Organization and the International Association of Diabetes and Pregnancy Study Group.

Keywords

• obesity
• pregnancy
• adipocytokines
• leptin
• adiponectin
• resistin
• gestational diabetes
• preeclampsia