An Innovative Liquid Biosensor for the Detection of Lipid Molecules Involved in Diseases of the Nervous System

Abstract

Growing evidence suggests that endocannabinoid levels are modulated during pathological conditions affecting both central and peripheral nervous system. In the present study, a novel approach (patent pending) based on an innovative liquid biosensor has been used to analyze two relevant endocannabinoid molecules with calibration purposes: N-arachidonoylethanolamine and 2-arachidonoylglycerol. The system was able to predict both compound concentrations with a Root Mean Square Error in Cross Validation (RMSECV) of 6.61 nM and 23.50 nM, respectively.

Keywords

• endocannabinoids
• biosensor
• BIONOTE