2-(Aminomethyl)benzimidazole/Cu²⁺ immobilized on Fe₃O₄@SiO₂: a convenient magnetic nanocatalyst for click reaction of aryl iodide/benzyl halide, sodium azide and terminal alkyne

Abstract

In this work, the Fe3O4@SiO2@AMBI/Cu nanocatalyst was synthesized and used as a well-organized magnetic nanocatalyst for the click reaction. This nanocatalyst has effectively catalyzed the cyclization of terminal alkynes and sodium azide with aryl iodide/benzyl halide for the formation of 1,4-disubstituted 1,2,3-triazoles under mild reaction conditions with good to high yields in low reaction time.

Keywords

• Click reaction
• Copper
• 2-(Aminomethyl)benzimidazole dihydrochloride
• Fe3O4@SiO2
• 1
• 4-disubstituted 1
• 2
• 3-triazoles