Детские инфекции (Москва) (Sep 2015)

BIOLOGYCAL IMUNOMODULATORS IN THE COMPLEX THERAPY OF INFECTIOUS MONONUCLEOSIS IN CHILDREN

  • A. G. Bokovoy,
  • I. V. Kovalev,
  • L. F. Makkaveeva,
  • O. A. Volodina,
  • A. A. Komarov,
  • A. Yu. Medkova,
  • N. B. Tanina

DOI
https://doi.org/10.22627/2072-8107-2015-14-1-3-8
Journal volume & issue
Vol. 14, no. 1
pp. 30 – 35

Abstract

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80 patients were observed with infectious mononucleosis (IM) from 2 to 12 years. Diagnosis was confirmed by the definition of M- and G-antibodies to EBV, CMV, HHV6, PCR DNA these viruses, bacteriological and blood-tests investigations. 40 patients was given bifidumbacterin forte 45—90 doses a day and cycloferon 8 mg/kg/weight a day(1-st group). The comparison group consisted of 40 patients with IM receiving symptomatic therapy and antibiotics (2-nd group). The observations shoved significant decreasing of length of clinical symptoms IM in the 1-st group with comparison of the 2-nd group. The obtained results allow to recommend bifidumbacterin forte and cycloferon in the complex therapy in children with infectious mononucleosis.

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