Neuropsychiatric Disease and Treatment (Dec 2019)

Type C Personality and Depression Among Newly Diagnosed Breast Cancer Patients: The Mediating Role of Sense of Coherence

  • Wei M,
  • Guo L,
  • Zhu Y,
  • Guo Y,
  • Yv S,
  • Namassevayam G,
  • Xue W,
  • Li J,
  • Li L,
  • Shen Z,
  • Yv J,
  • Zhu Z,
  • Wang W,
  • Liu Y,
  • Zhao J,
  • Chen F

Journal volume & issue
Vol. Volume 15
pp. 3519 – 3529

Abstract

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Miao Wei,1 Lina Guo,1 Yiru Zhu,1 Yvru Guo,2 Suyuan Yv,1 Genoosha Namassevayam,1 Wenhua Xue,3 Jieyao Li,4 Lifeng Li,4 Zhibo Shen,4 Junlin Yv,4 Zijia Zhu,3 Wenbin Wang,3 Yanjin Liu,5 Jie Zhao,3 Fu Chen6 1Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People’s Republic of China; 2Department of Orthopedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People’s Republic of China; 3Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People’s Republic of China; 4Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People’s Republic of China; 5Department of Nursing, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People’s Republic of China; 6Department of Medical Administration, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People’s Republic of ChinaCorrespondence: Yanjin LiuDepartment of Nursing, The First Affiliated Hospital of Zhengzhou University, PO Box 450052, Zhengzhou, Henan Province, People’s Republic of ChinaEmail [email protected] ZhaoDepartment of Pharmacy, The First Affiliated Hospital of Zhengzhou University, PO Box 450052, Zhengzhou, Henan Province, People’s Republic of ChinaEmail [email protected]: This study aims to explore the mediating role of sense of coherence in the relationship of type C personality and depression among newly diagnosed breast cancer patients.Methods: A descriptive and correlational survey was conducted in 600 breast cancer patients aged ≥18 years from September 2018 to March 2019 in Zhengzhou, China. The demographic questionnaire, Cancer Behavior Scale, Sense of Coherence Scale and Hamilton Depression Scale were included in this study. Data analysis was performed by correlation analysis, multiple linear regression analysis, and structural equation modeling.Results: The valid questionnaires were 575 (effective response rate: 95.8%). The score of sense of coherence was negatively correlated with type C personality and depression (r = −0.41, P < 0.01; r = −0.58, P < 0.01); the score of type C personality and depression were positively correlated (r = 0.51, P < 0.01). The results of multiple linear regression analysis revealed that the effect of type C personality on depression was partly mediated by sense of coherence, which was confirmed by structural equation modeling. The mediation effect accounts for 45.2% (0.269/0.594) of the total effect.Conclusion: The results of this study revealed that sense of coherence as a partial mediating role is essential for reducing the influence of type C personality on depression. Early and targeted psychological interventions on sense of coherence are needed to alleviate the symptom of depression in newly diagnosed breast cancer patients.Keywords: breast cancer, sense of coherence, type C personality, depression, mediation effect

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