P329: HIGH IMMUNOPROTEASOME ACTIVITY AS NOVEL INDICATOR FOR SENSITIVITY TO BORTEZOMIB-CONTAINING CHEMOTHERAPY IN ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS FROM CHILDREN’S ONCOLOGY GROUP TRIAL AALL1231

• Margot Roeten,
• Suzanne van Dijk,
• Johan van Meerloo,
• Zinia Kwidama,
• Gaya Jenkins,
• David Teachey,
• Meenakshi Devidas,
• Mignon Loh,
• Gertjan Kaspers,
• Sonja Zweegman,
• Gerrit Jansen,
• Terzah Horton,
• Jacqueline Cloos

Affiliations

Margot Roeten

1 Amsterdam UMC, location Vrije Universiteit, Department of Hematology, Amsterdam, The Netherlands

Suzanne van Dijk

1 Amsterdam UMC, location Vrije Universiteit, Department of Hematology, Amsterdam, The Netherlands

Johan van Meerloo

1 Amsterdam UMC, location Vrije Universiteit, Department of Hematology, Amsterdam, The Netherlands

Zinia Kwidama

1 Amsterdam UMC, location Vrije Universiteit, Department of Hematology, Amsterdam, The Netherlands

Gaya Jenkins

2 Texas Children’s Hospital, Department of Pediatrics, Baylor College of Medicine, Houston, United States

David Teachey

3 Children’s Hospital of Philadelphia and The Perelman School of Medicine at The University of Pennsylvania, Department of Pediatrics and the Center for Childhood Cancer Research, Philadelphia, United States

Meenakshi Devidas

4 St Jude Children’s Research Hospital, Department of Global Pediatric Medicine, Memphis, United States

Mignon Loh

5 Seattle Children’s Hospital, Division of Hematology, Oncology, BMT, and Cellular Therapies, Seattle, United States

Gertjan Kaspers

6 Princess Máxima Center of Pediatric Oncology, Utrecht, The Netherlands

Sonja Zweegman

8 Amsterdam UMC, location Vrije Universiteit, Department of Hematology, Amsterdam, The Netherlands

Gerrit Jansen

9 Amsterdam UMC, location Vrije Universiteit, Rheumatology and Immunology Center, Amsterdam, The Netherlands

Terzah Horton

2 Texas Children’s Hospital, Department of Pediatrics, Baylor College of Medicine, Houston, United States

Jacqueline Cloos

1 Amsterdam UMC, location Vrije Universiteit, Department of Hematology, Amsterdam, The Netherlands