Efeito da ingestão de fumonisina B1 no peso corporal e na histopatologia de codornas japonesas (Coturnix coturnix japonica) Effect of fumonisin B1 on body weight and histopathology of Japanese quail (Coturnix coturnix japonica)

Abstract

O objetivo do presente trabalho foi estudar o efeito da fumonisina B1 (FB1) sobre o peso corpóreo e as vísceras (fígado, rim e coração) de codorna poedeira japonesa (Coturnix coturnix japonica), devido ao escasso dado toxicológico nesta espécie. Quatro grupos, sendo cada um constituído de 32 codornas de linhagem comercial, receberam ração contendo FB1 nas concentrações de 0 (controle), 10, 50 e 250mg kg-1, durante 28 dias. Observou-se uma redução (P0,05), porém as aves do grupo 50 e 250mg kg-1 apresentaram aumento no peso relativo de fígado (PThis research was aimed at evaluating the effect of fumonisin B1 (FB1) on body weight and viscera (liver, kidney and heart) of laying Japanese quail (Coturnix coturnix japonica), due to the little toxicological data on this species. Four experimental groups of 32 commercial quails were designed and exposed to ingestion test with feed containing 0 (controls), 10, 50 or 250mg FB1 kg-1 feed, during 28 days. Birds of group 250mg FB1 kg-1 showed lower body weight (P0.05) among treatments. However, the relative weight of liver increased (P<0.05) in quail of groups received 50 and 250mg FB1/kg. Histological changes were observed only in the liver of groups receiving 50 and 250mgFB1 kg-1, which caused moderate biliary duct hyperplasia and multiple foci of hepatic necrosis. The data indicated that AFB1 at levels above 50mg kg-1 in laying Japanese quail.

Keywords

• FB1
• toxicidade
• alterações histopatológicas
• codorna
• FB1
• toxicity
• histopathology
• quail