524 Tim-4+ resident macrophages impair anti-tumor immunity in the serous body cavities By sequestering viable and cytotoxic CD8+ T cells expressing high levels of phosphatidylserine

• Michael Green,
• Dmitriy Zamarin,
• Katherine Panageas,
• Taha Merghoub,
• Weiping Zou,
• Cailian Liu,
• Jedd Wolchok,
• Matthew Hellmann,
• Joseph Chan,
• Hongyu Shi,
• Hira Rizvi,
• Jessica Waninger,
• Aditi Gupta,
• Nicholas Ceglia,
• Viola Allaj,
• Giulia Zago,
• Nisarg Shah,
• Sai Sharma,
• Marissa Mattar,
• Yonina Bykov,
• Corrin Wohlhieter,
• Fathema Uddin,
• Inna Khodos,
• Angel Qin,
• Vinod Balachandran,
• Sohrab Shah,
• Andrew McPherson,
• Jason Lewis,
• Justin Perry,
• Elisa de Stanchina,
• Triparna Sen,
• John Poirier,
• Charles Rudin

Affiliations

Michael Green

The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Dmitriy Zamarin

Memorial Sloan Kettering Cancer Center, New York City, New York, USA

Katherine Panageas

Aff1 grid.51462.340000000121719952Memorial Sloan Kettering Cancer Center New York NY USA

Taha Merghoub

1Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Weiping Zou

Aff2 grid.214458.e0000000086837370Dept. of SurgeryImmunology, Biology, University of Michigan Ann Arbor MI USA

Cailian Liu

1Memorial Sloan-Kettering Cancer Center, New York, NY, USA

Jedd Wolchok

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Matthew Hellmann

Aff1 grid.51462.340000000121719952Memorial Sloan Kettering Cancer Center New York NY USA

Joseph Chan

Aff3 0000 0004 1936 8606grid.26790.3aDepartment of Medicine, Division of Infectious DiseasesUniversity of Miami Miller School of Medicine, Mount Sinai Medical Center Miami USA

Hongyu Shi

School of Nursing, Jilin University, Changchun, Jilin, China

Hira Rizvi

7 Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York, USA

Jessica Waninger

University of Michigan, Ann Arbor, MI, USA

Aditi Gupta

Division of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, Kansas, USA

Nicholas Ceglia

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Viola Allaj

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Giulia Zago

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Nisarg Shah

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Sai Sharma

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Marissa Mattar

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Yonina Bykov

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Corrin Wohlhieter

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Fathema Uddin

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Inna Khodos

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Angel Qin

2University of Michigan, Ann Arbor, MI, USA

Vinod Balachandran

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Sohrab Shah

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Andrew McPherson

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Jason Lewis

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Justin Perry

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Elisa de Stanchina

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

Triparna Sen

1Memorial Sloan Kettering Cancer Center, New York, NY, USA

John Poirier

3NYU Langone Medical Center, New York, NY, USA

Charles Rudin

1Memorial Sloan Kettering Cancer Center, New York, NY, USA