Nature Communications (Nov 2017)
Intranasal infection and contact transmission of Zika virus in guinea pigs
- Yong-Qiang Deng,
- Na-Na Zhang,
- Xiao-Feng Li,
- Ya-Qing Wang,
- Min Tian,
- Ye-Feng Qiu,
- Jun-Wan Fan,
- Jia-Nan Hao,
- Xing-Yao Huang,
- Hao-Long Dong,
- Hang Fan,
- Yu-Guang Wang,
- Fu-Chun Zhang,
- Yi-Gang Tong,
- Zhiheng Xu,
- Cheng-Feng Qin
Affiliations
- Yong-Qiang Deng
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- Na-Na Zhang
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- Xiao-Feng Li
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- Ya-Qing Wang
- State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
- Min Tian
- Beijing Traditional Chinese Medicine Hospital, Capital Medical University
- Ye-Feng Qiu
- Laboratory Animal Center, Academy of Military Medical Science
- Jun-Wan Fan
- State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
- Jia-Nan Hao
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- Xing-Yao Huang
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- Hao-Long Dong
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- Hang Fan
- State Key Laboratory of Pathogen and Biosecurity
- Yu-Guang Wang
- Beijing Traditional Chinese Medicine Hospital, Capital Medical University
- Fu-Chun Zhang
- Guangzhou Eighth People’s Hospital, Guangzhou Medical University
- Yi-Gang Tong
- State Key Laboratory of Pathogen and Biosecurity
- Zhiheng Xu
- State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
- Cheng-Feng Qin
- Department of Virology, Beijing Institute of Microbiology and Epidemiology
- DOI
- https://doi.org/10.1038/s41467-017-01923-4
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 8
Abstract
Human case studies suggest that Zika virus can be transmitted independently of mosquitoes and sexual contact. Here, the authors show intranasal Zika infection in different animal models and show that contact transmission of Zika virus occurs in guinea pigs.