Subcortical-cortical dynamical states of the human brain and their breakdown in stroke

Chiara Favaretto; Michele Allegra; Gustavo Deco; Nicholas V. Metcalf; Joseph C. Griffis; Gordon L. Shulman; Andrea Brovelli; Maurizio Corbetta

doi:10.1038/s41467-022-32304-1

Nature Communications (Aug 2022)

Subcortical-cortical dynamical states of the human brain and their breakdown in stroke

Chiara Favaretto,
Michele Allegra,
Gustavo Deco,
Nicholas V. Metcalf,
Joseph C. Griffis,
Gordon L. Shulman,
Andrea Brovelli,
Maurizio Corbetta

Affiliations

Chiara Favaretto: Padova Neuroscience Center (PNC), University of Padova
Michele Allegra: Padova Neuroscience Center (PNC), University of Padova
Gustavo Deco: Center for Brain and Cognition (CBC), Department of Information Technologies and Communications (DTIC), Pompeu Fabra University, Edifici Mercè Rodoreda
Nicholas V. Metcalf: Department of Neurology, Washington University School of Medicine
Joseph C. Griffis: Department of Neurology, Washington University School of Medicine
Gordon L. Shulman: Department of Neurology, Washington University School of Medicine
Andrea Brovelli: Institut de Neurosciences de la Timone UMR 7289, Aix Marseille Université, CNRS
Maurizio Corbetta: Padova Neuroscience Center (PNC), University of Padova

DOI: https://doi.org/10.1038/s41467-022-32304-1
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 17

Abstract

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Favaretto et al. show that the brain rapidly alternates between transient connectivity patterns, with cortical regions flexibly synchronizing with two groups of subcortical regions, and that this dynamic is abnormal in stroke patients.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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