Communications Biology (Oct 2021)

Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma

  • Sunetra Das,
  • Rupa Idate,
  • Daniel P. Regan,
  • Jared S. Fowles,
  • Susan E. Lana,
  • Douglas H. Thamm,
  • Daniel L. Gustafson,
  • Dawn L. Duval

DOI
https://doi.org/10.1038/s42003-021-02683-0
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 15

Abstract

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Sunetra Das et al. combine genetic and immunohistochemistry data to characterize mutation and expression profiles of canine osteosarcoma and its association with clinical outcomes. Their results provide further insight into the pathogenesis and potential future therapeutic targets for osteosarcoma.