Evaluation of Non-invasive Mechanical Vventilation Methods in Preterm İnfants

Abstract

INTRODUCTION: Non-invasive ventilation provides ventilation support without the need to establish an artificial airway. It reduces the need for invasive mechanical ventilation, surfactant replacement and oxygen supplementation in preterms. We aimed to compare the success of non-invasive ventilation practices to prevent intubation in very low birth weight preterm infants. METHODS: Patients who were followed in the third level neonatal intensive care unit between January 2017-2019, who had ≤32 weeks gestation years, who did not need intubation in the delivery room, who had RDS and non-invasive ventilation were included in the study. Patients were divided into two groups: Nasal Continuous Positive Airway Pressure (NCPAP) and Nasal intermittent positive pressure ventilation (NIPPV). The primary result; postnatal intubation requirement was determined in the first week. Data were evaluated retrospectively. RESULTS: A total of 134 patients were included in our study. Of the patients, 85 (63.4%) were in NCPAP and 49 (36.6%) were in NIPPV mode.There were no differences between the groups in terms of birth weight, gestation week, gender, type of delivery. Non-invasive ventilation failure was 40% in the NCPAP group and 53% in the NIPPV group and no significant difference was found between the groups (p = 0.14). The rate of pneumothorax was higher in the NIPPV group and the duration of total mechanical ventilation was lower. There were no significant differences in mid-term morbidities between PDA, IVH, PVL and NEC. The duration of hospitalization was similar. DISCUSSION AND CONCLUSION: In our NCPAP and NIPPV study, the primary result was not superior in preventing intubation.

Keywords

• ncpap
• nsippv
• preterm