Gastroenterology Research and Practice (Jan 2017)

Magnifying Endoscopy with Blue Laser Imaging Improves the Microstructure Visualization in Early Gastric Cancer: Comparison of Magnifying Endoscopy with Narrow-Band Imaging

  • Reiko Kimura-Tsuchiya,
  • Osamu Dohi,
  • Yasuko Fujita,
  • Nobuaki Yagi,
  • Atsushi Majima,
  • Yusuke Horii,
  • Tomoko Kitaichi,
  • Yuriko Onozawa,
  • Kentaro Suzuki,
  • Akira Tomie,
  • Tetsuya Okayama,
  • Naohisa Yoshida,
  • Kazuhiro Kamada,
  • Kazuhiro Katada,
  • Kazuhiko Uchiyama,
  • Takeshi Ishikawa,
  • Tomohisa Takagi,
  • Osamu Handa,
  • Hideyuki Konishi,
  • Mitsuo Kishimoto,
  • Yuji Naito,
  • Akio Yanagisawa,
  • Yoshito Itoh

DOI
https://doi.org/10.1155/2017/8303046
Journal volume & issue
Vol. 2017

Abstract

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Backgrounds. Magnifying endoscopy with blue laser imaging (ME-BLI) for diagnosis of early gastric cancer (EGC) is as effective as magnifying endoscopy with narrow-band imaging (ME-NBI). However, there are different EGCs in microstructure visualization between ME-BLI and ME-NBI. This study aimed to clarify the pathological features of the EGCs, in which microstructure visualization was different between ME-NBI and ME-BLI. Methods. EGCs were classified into groups A (irregular microsurface pattern (MSP) in ME-BLI and absent MSP in ME-NBI), B (irregular MSP in two modalities), or C (absent MSP in two modalities), according to the vessel plus surface classification. We compared the pathological features of EGCs between the three groups. Results. 17, four, and five lesions could be evaluated in detail in groups A, B and C, respectively. Well-differentiated adenocarcinomas with shallow crypts were more frequent in group A than in group B (58.8 and 0%, resp.). The mean crypt depth of group A was significantly shallower than that of group B (56 ± 20, 265 ± 64 μm, resp., P=0.0002). Conclusions. ME-BLI could better visualize the microstructures of the EGCs with shallow crypts compared with ME-NBI. Therefore, ME-BLI could enable a more accurate diagnosis of EGC with shallow crypts.