Improving Alzheimer’s Detection With Deep Learning and Image Processing Techniques

Abstract

Alzheimer’s Disease (AD) is characterized by the gradual degeneration and decline of brain cells, leading to irreversible neurological changes. This study investigates advanced image enhancement techniques for improving AD diagnosis using brain MRI. The methods used include CLAHE (Contrast Limited Adaptive Histogram Equalization) to enhance local image contrast and ESRGAN (Enhanced Super-Resolution Generative Adversarial Networks) to improve image resolution. These preprocessing methods improve MRI images and classification accuracy. An ensemble model of MobileNetV2 and DenseNet121, two efficient deep-learning models with feature extraction capabilities, were used as classifiers. This approach addresses challenges in AD diagnosis by leveraging deep learning for more accurate classification of brain tissue images. The model achieved an accuracy of 80.31% for MobileNetV2 and 89.22% for DenseNet121 when no enhancements were utilized. The model achieved accuracies of 92.34% and 89.38% for MobileNetV2 and DenseNet121, respectively, when enhancement methods were utilized, indicating strong dependability with the Kaggle dataset of MRI images. These findings underscore the efficacy of advanced image processing and deep learning in the early and accurate detection of Alzheimer’s disease.

Keywords

• Alzheimer’s
• computer-aided diagnosis
• deep learning
• DenseNet121
• image enhancement
• MobileNetV2