AP-1 Transcription Factor Complex Members FOSB and FOS are Linked With CNS Infiltration and Inferior Prognosis in Childhood T-ALL

• Lea Spory,
• Johannes Zimmermann,
• Michaela Vossen-Gajcy,
• Thomas Beder,
• Lorenz Bastian,
• Ameera Alsadeq,
• Dorothee Winterberg,
• Fotini Vogiatzi,
• Tim Wirbelauer,
• Hilal Bhat,
• Arndt Borkhardt,
• Sanil Bhatia,
• Martin Schrappe,
• Gunnar Cario,
• Denis M. Schewe,
• Lennart Lenk

Affiliations

Lea Spory

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany

Johannes Zimmermann

2 Department of Evolutionary Ecology and Genetics, Zoological Institute, University of Kiel, Germany

Michaela Vossen-Gajcy

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany

Thomas Beder

3 Medical Department II, Haematology and Oncology, University Medical Centre Schleswig-Holstein, Kiel, Germany

Lorenz Bastian

3 Medical Department II, Haematology and Oncology, University Medical Centre Schleswig-Holstein, Kiel, Germany

Ameera Alsadeq

4 Institute of Immunology, Ulm University Medical Centre, Ulm, Germany

Dorothee Winterberg

5 Division of Antibody-Based Immunotherapy, Department of Medicine II, Christian Albrechts University Kiel and University Medical Centre Schleswig-Holstein, Germany

Fotini Vogiatzi

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany

Tim Wirbelauer

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany

Hilal Bhat

6 Faculty of Medicine, Otto-von-Guericke University, Magdeburg, Germany

Arndt Borkhardt

7 Department of Paediatric Oncology, Haematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Germany

Sanil Bhatia

7 Department of Paediatric Oncology, Haematology and Clinical Immunology, Medical Faculty, Heinrich Heine University Düsseldorf, Germany

Martin Schrappe

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany

Gunnar Cario

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany

Denis M. Schewe

6 Faculty of Medicine, Otto-von-Guericke University, Magdeburg, Germany

Lennart Lenk

1 Department of Paediatrics I, Paediatric Haematology/Oncology, ALL-BFM Study Group, University Medical Centre Schleswig-Holstein, Kiel, Germany