Antibacterial Property and Cytotoxicity of a Poly(lactic acid)/Nanosilver-Doped Multiwall Carbon Nanotube Nanocomposite

Chi-Hui Tsou; Wei-Hua Yao; Yi-Cheng Lu; Chih-Yuan Tsou; Chin-San Wu; Jian Chen; Ruo Yao Wang; Chaochin Su; Wei-Song Hung; Manuel De Guzman; Maw-Cherng Suen

doi:10.3390/polym9030100

Polymers (Mar 2017)

Antibacterial Property and Cytotoxicity of a Poly(lactic acid)/Nanosilver-Doped Multiwall Carbon Nanotube Nanocomposite

Chi-Hui Tsou,
Wei-Hua Yao,
Yi-Cheng Lu,
Chih-Yuan Tsou,
Chin-San Wu,
Jian Chen,
Ruo Yao Wang,
Chaochin Su,
Wei-Song Hung,
Manuel De Guzman,
Maw-Cherng Suen

Affiliations

Chi-Hui Tsou: Material Corrosion and Protection Key Laboratory of Sichuan Province, College of Materials Science and Engineering, Sichuan University of Science and Engineering, Zigong 643000, China
Wei-Hua Yao: Department of Materials and Textiles, Oriental Institute of Technology, New Taipei City 22061, Taiwan
Yi-Cheng Lu: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
Chih-Yuan Tsou: Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan
Chin-San Wu: Department of Applied Cosmetology, Kao Yuan University, Kaohsiung 82101, Taiwan
Jian Chen: Material Corrosion and Protection Key Laboratory of Sichuan Province, College of Materials Science and Engineering, Sichuan University of Science and Engineering, Zigong 643000, China
Ruo Yao Wang: Department of Molecular Science & Engineering, National Taipei University of Technology, Taipei 10608, Taiwan
Chaochin Su: Department of Molecular Science & Engineering, National Taipei University of Technology, Taipei 10608, Taiwan
Wei-Song Hung: Center for Membrane Technology, Chung Yuan University, Taoyuan 32023, Taiwan
Manuel De Guzman: Center for Membrane Technology, Chung Yuan University, Taoyuan 32023, Taiwan
Maw-Cherng Suen: Department of Fashion Business Administration, Lee-Ming Institute of Technology, Taishan, New Taipei City 24305, Taiwan

DOI: https://doi.org/10.3390/polym9030100
Journal volume & issue: Vol. 9, no. 3
p. 100

Abstract

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A novel method was used to synthesize a nanosilver-doped multiwall carbon nanotube (MWCNT-Ag), and subsequently, the novel poly(lactic acid) (PLA)- and MWCNT-Ag-based biocompatible and antimicrobial nanocomposites were prepared by melt blending. Based on energy dispersive X-ray spectrometry images, an MWCNT-Ag was successfully synthesized. The effect of the MWCNT-Ag on the PLA bionanocomposites was investigated by evaluating their thermal and mechanical properties, antifungal activity, and cytotoxicity. The nanocomposites exhibited a high degree of biocompatibility with the MWCNT-Ag content, which was less than 0.3 phr. Furthermore, tensile strength testing, thermogravimetric analysis, differential scanning calorimetry, and antibacterial evaluation revealed that the tensile strength, thermostability, glass transition temperature, and antibacterial properties were enhanced by increasing the MWCNT-Ag content. Finally, hydrolysis analysis indicated that the low MWCNT-Ag content could increase the packing density of PLA.

Published in Polymers

ISSN: 2073-4360 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/polymers/

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