Онкогематология (Jul 2014)

Comparative efficacy of acute lymphoblastic leukemia treatment of children in St.-Petersburg using two COALL-92 versions

  • E. G. Boychenko,
  • E. M. Petrova,
  • I. A. Garbuzova,
  • E. A. Nikitina,
  • L. M. Shchugareva,
  • T. N. Kulakova,
  • T. A. Makarova,
  • M. B. Belogurova,
  • G. G. Radulesku,
  • T. D. Viktorovich,
  • E. D. Chavpetsova,
  • L. I. Shats,
  • G. I. Uleyskaya,
  • I. S. Martynkevich,
  • E. E. Zueva

Journal volume & issue
Vol. 6, no. 3
pp. 8 – 17

Abstract

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Treatment results in children with acute lymphoblastic leukemia (ALL) treating in St.-Petersburg hospitals according to two modified version of German protocol CO ALL-92 from 01.01.1993 to 01.01.2007 are presented. 438 primary A LL patients aged from 4 months to 17 year s have been included in the study . ALL diagnosed according to international criteria. Based on prognostic factors patients were a llocated to one of two risk groups, which determined therapy intensity . The total treatment duration in both groups w as 2 years and consist ed of 5.5–8 months intensive phase with subsequent maintenance therapy . A comparative treatment results analysis in children with A LL according to two modified versions of COALL-92 is presented.

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