Sesterterpenes and a New Sterol from the Marine Sponge Phyllospongia foliascens

Abstract

A new scalarane sesterterpene, phyllofolactone M (1), and a new sterol, (24E)-5α,6α-epoxystigmasta-7,24(28)-dien-3β-ol (3), together with a known sesterterpene, phyllofolactone B (2), were isolated from the South China Sea sponge Phyllospongia foliascens. Their structures were elucidated by spectroscopic analysis and comparison with known compounds. In addition, previous NMR data assignments for the known sesterterpene phyllofolactone B (2) were revised.

Keywords

• sesterterpene
• sterol
• marine sponge
• Phyllospongia foliascens