A Sensitive Gold Nanoplasmonic SERS Quantitative Analysis Method for Sulfate in Serum Using Fullerene as Catalyst
Chongning Li,
Libing Wang,
Yanghe Luo,
Aihui Liang,
Guiqing Wen,
Zhiliang Jiang
Affiliations
Chongning Li
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, (Guangxi Normal University), Ministry of Education, Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China
Libing Wang
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, (Guangxi Normal University), Ministry of Education, Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China
Yanghe Luo
School of Food and Bioengineering, Hezhou University, Hezhou 542899, China
Aihui Liang
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, (Guangxi Normal University), Ministry of Education, Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China
Guiqing Wen
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, (Guangxi Normal University), Ministry of Education, Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China
Zhiliang Jiang
Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, (Guangxi Normal University), Ministry of Education, Guangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin 541004, China
Fullerene exhibited strong catalysis of the redox reaction between HAuCl4 and trisodium citrate to form gold nanoplasmon with a strong surface-enhanced Raman scattering (SERS) effect at 1615 cm−1 in the presence of Vitoria blue B molecule probes. When fullerene increased, the SERS peak enhanced linearly due to formation of more AuNPs as substrate. Upon addition of Ba2+, Ba2+ ions adsorb on the fullerene surface to inhibit the catalysis of fullerene that caused the SERS peak decreasing. Analyte SO42− combined with Ba2+ to form stable BaSO4 precipitate to release free fullerene that the catalysis recovered, and the SERS intensity increased linearly. Thus, a new SERS quantitative analysis method was established for the detection of sulfate in serum samples, with a linear range of 0.03–3.4 μM.
