Спортивная медицина: наука и практика (Jun 2021)

Frequency of occurrence of genetic polymorphisms associated with sports success in elite athletes in team sports

  • E. Yu. Sorokina,
  • N. N. Denisova,
  • E. E. Keshabyants

DOI
https://doi.org/10.47529/2223-2524.2021.1.11
Journal volume & issue
Vol. 11, no. 1
pp. 5 – 10

Abstract

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Objective: to evaluate the frequency of occurrence of polymorphisms rs1815739 (ACTN3 gene), rs2016520 (PPARD gene), rs1042713 (ADRB2 gene), rs1799945 (HFE gene) in athletes of high­performance sports.Materials and methods: genotyping was performed using allele­specific amplification with real­time detection of the results and using TaqMan probes.Results: a higher frequency of alleles associated with endurance was found: the t allele of the rs1815739 polymorphism (ACTN3 gene), the g allele of the rs2016520 polymorphism (PPARD gene), the g allele of the rs1042713 polymorphism (ADRB2 gene), and the g allele of the rs1799945 polymorphism (HFE gene) in athletes of game sports.Conclusion: the results of genotyping of polymorphisms associated with endurance in the examined athletes showed a higher frequency of occurrence than in the population as a whole.

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