Training ANFIS structure using genetic algorithm for liver cancer classification based on microarray gene expression data

Abstract

Classification is an important data mining technique, which is used in many fields mostly exemplified as medicine, genetics and biomedical engineering. The number of studies about classification of the datum on DNA microarray gene expression is specifically increased in recent years. However, because of the reasons as the abundance of gene numbers in the datum as microarray gene expressions and the nonlinear relations mostly across those datum, the success of conventional classification algorithms can be limited. Because of these reasons, the interest on classification methods which are based on artificial intelligence to solve the problem on classification has been gradually increased in recent times. In this study, a hybrid approach which is based on Adaptive Neuro-Fuzzy Inference System (ANFIS) and Genetic Algorithm (GA) are suggested in order to classify liver microarray cancer data set. Simulation results are compared with the results of other methods. According to the results obtained, it is seen that the recommended method is better than the other methods.

Keywords

• Neuro-fuzzy
• ANFIS
• genetic algorithm
• classification
• microarray gene expression