Invasive infection caused by Geotrichum capitatum in three patients with acute myeloid leukemia

Abstract

Geotrichum capitatum is an uncommon cause of invasive infections in immunocompromised patients. We report three cases of Geotrichum capitatum fungemia in neutropenic patients receiving chemotherapy for acute myeloid leukemia. All the three patients were neutropenic and presented a history of febrile sepsis not responding to broad-spectrum antibiotic therapy. The evolution under antifungal treatment was favorable in one case and the other two patients died one of failure of several organs and the other of acute respiratory distress syndrome.

Keywords

• acute myeloid leukemia
• neutropenia
• geotrichum capitatum
• case report