Chimica Techno Acta (Dec 2020)

Molecular Complexation of Hederasaponin C with Cholesterol in Aqueous Isopropyl Alcohol

  • L. A. Yakovishin,
  • V. I. Grishkovets,
  • E. N. Korzh,
  • I. V. Golovchenko,
  • A. A. Nagirnyak

DOI
https://doi.org/10.15826/chimtech.2020.7.4.02
Journal volume & issue
Vol. 7, no. 4
pp. 150 – 153

Abstract

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The 1:1 molecular complex of ivy triterpene glycoside hederasaponin C (HedC) with cholesterol (Chol) was obtained in aqueous isopropyl alcohol. The stability constant of (3.3 ± 0.7)∙106 (mol/L)–1 was calculated for the complex. The complexation was studied by UV- and ATR IR-Fourier spectroscopy, and method of isomolar series. The hydrogen bonds and hydrophobic interactions are formed in the molecular complex.

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