Scientific Reports (Apr 2024)

Population-based retrospective cohort study on community-acquired pneumonia hospitalization in children with a ventricular septal defect

  • Myongsoon Sung,
  • Ju Hee Kim,
  • Eun Kyo Ha,
  • Jeewon Shin,
  • Ji Hee Kwak,
  • Hye Mi Jee,
  • Man Yong Han

DOI
https://doi.org/10.1038/s41598-024-59510-9
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 10

Abstract

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Abstract The cohort consisted of 9400 exposed children diagnosed with ventricular septal defect (VSD). The risk of community-acquired pneumonia (CAP) or asthma with VSD was assessed using the Cox proportional hazard model with an inverse probability of treatment weighting. During a mean follow-up of 6.67 years (starting from 12 months after birth), there were 2100 CAP admission cases among exposed patients (incidence rate: 33.2 per 1000 person-years) and 20,109 CAP admission cases among unexposed children (incidence rate: 29.6 per 1000 person-years), with hazard ration of 1.09 (95% CI 1.04–1.14).