Nature Communications (Dec 2018)

MoVE identifies metabolic valves to switch between phenotypic states

  • Naveen Venayak,
  • Axel von Kamp,
  • Steffen Klamt,
  • Radhakrishnan Mahadevan

DOI
https://doi.org/10.1038/s41467-018-07719-4
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 9

Abstract

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Interventions in metabolic networks can improve microbes for chemical production. Here, the authors develop a tool to identify metabolic valves that can decouple growth and production to systematically improve the rate and yield of biochemical production processes.