Epidemiological study of insular glioma – an institutional experience

Abstract

Object: Insular gliomas are difficult and challenging tumors to operate and manage due to the inherent complexity and the adjacent vital structures around them. Our aim is to define the morbidity profile and the mortality associated with the maximum possible safe resection of these less common tumors. Methods: The study was conducted on patients who were diagnosed as insular gliomas on MRI. All grades of patients treated by microsurgical techniques at our center from 2010 to 2016 were included in the study. Results: Median age at diagnosis was 39.52 years, Mean KPS score was 92.Male patients constituted 23 of all patients.68% patients had right sided tumors.WHO grade 2 was most common grade and constituted 64% of all cases.One patient developed expressive aphasia and five patients developed hemiparesis .There was one mortality due to unrelated causes. Conclusion: With the use of meticulous microneurosurgical technique, safe yet aggressive resection of the insular gliomas can be accomplished with comparable morbidity and mortality rates even when the modern neurosurgical tool such as intraoperative neuromonitoring and neuronavigation systems are unavailable.

Keywords

• Insular glioma
• Microneurosurgery
• Intraoperative neuronavigation