Mechanism of fibroblast growth factor 21 in cardiac remodeling

Zeyu Zhao; Xuemei Cui; Zhangping Liao

doi:10.3389/fcvm.2023.1202730

Frontiers in Cardiovascular Medicine (Jun 2023)

Mechanism of fibroblast growth factor 21 in cardiac remodeling

Zeyu Zhao,
Xuemei Cui,
Zhangping Liao

Affiliations

Zeyu Zhao: Queen Mary College, Nanchang University, Nanchang, China
Xuemei Cui: Fourth Clinical Medical College, Nanchang University, Nanchang, China
Zhangping Liao: Jiangxi Provincial Key Laboratory of Basic Pharmacology School of Pharmaceutical Science, Nanchang University, Nanchang, China

DOI: https://doi.org/10.3389/fcvm.2023.1202730
Journal volume & issue: Vol. 10

Abstract

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Cardiac remodeling is a basic pathological process that enables the progression of multiple cardiac diseases to heart failure. Fibroblast growth factor 21 is considered a regulator in maintaining energy homeostasis and shows a positive role in preventing damage caused by cardiac diseases. This review mainly summarizes the effects and related mechanisms of fibroblast growth factor 21 on pathological processes associated with cardiac remodeling, based on a variety of cells of myocardial tissue. The possibility of Fibroblast growth factor 21 as a promising treatment for the cardiac remodeling process will also be discussed.

Published in Frontiers in Cardiovascular Medicine

ISSN: 2297-055X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.frontiersin.org/journals/cardiovascular-medicine

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