Nature Communications (Mar 2021)

Predicting the public health impact of a malaria transmission-blocking vaccine

  • Joseph D. Challenger,
  • Daniela Olivera Mesa,
  • Dari F. Da,
  • R. Serge Yerbanga,
  • Thierry Lefèvre,
  • Anna Cohuet,
  • Thomas S. Churcher

DOI
https://doi.org/10.1038/s41467-021-21775-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Malaria transmission-blocking vaccines are in development, but roll-out strategies have not been assessed. Here, the authors show that transmission-blocking activity is likely to be higher in the field than in laboratory conditions, and that school-aged children are an important group to target.