Biocatalytic Construction of Chiral Pyrrolidines and Indolines via Intramolecular C(sp3)–H Amination

• Zi-Yang Qin,
• Shilong Gao,
• Yike Zou,
• Zhen Liu,
• James B. Wang,
• Kendall N. Houk,
• Frances H. Arnold

Affiliations

Zi-Yang Qin

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United States

Shilong Gao

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United States

Yike Zou

Department of Chemistry and Biochemistry, University of Californi, Los Angeles, California, United States

Zhen Liu

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United States

James B. Wang

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United States

Kendall N. Houk

Department of Chemistry and Biochemistry, University of Californi, Los Angeles, California, United States

Frances H. Arnold

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United States