PLoS ONE (Jan 2022)

Resuscitative endovascular balloon occlusion of the aorta associated with improved survival in hemorrhagic shock.

  • Melike N Harfouche,
  • Marta J Madurska,
  • Noha Elansary,
  • Hossam Abdou,
  • Eric Lang,
  • Joseph J DuBose,
  • Rishi Kundi,
  • David V Feliciano,
  • Thomas M Scalea,
  • Jonathan J Morrison

DOI
https://doi.org/10.1371/journal.pone.0265778
Journal volume & issue
Vol. 17, no. 3
p. e0265778

Abstract

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BackgroundResuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) is controversial as a hemorrhage control adjunct due to lack of data with a suitable control group. We aimed to determine outcomes of trauma patients in shock undergoing REBOA versus no-REBOA.MethodsThis single-center, retrospective, matched cohort study analyzed patients ≥16 years in hemorrhagic shock without cardiac arrest (2000-2019). REBOA (R; 2015-2019) patients were propensity matched 2:1 to historic (H; 2000-2012) and contemporary (C; 2013-2019) groups. In-hospital mortality and 30-day survival were analyzed using chi-squared and log rank testing, respectively.ResultsA total of 102,481 patients were included (R = 57, C = 88,545, H = 13,879). Propensity scores were assigned using age, race, mechanism, lowest systolic blood pressure, lowest Glasgow Coma Score (GCS), and body region Abbreviated Injury Scale scores to generate matched groups (R = 57, C = 114, H = 114). In-hospital mortality was significantly lower in the REBOA group (19.3%) compared to the contemporary (35.1%; p = 0.024) and historic (44.7%; p = 0.001) groups. 30-day survival was significantly higher in the REBOA versus no-REBOA groups.ConclusionIn a high-volume center where its use is part of a coordinated hemorrhage control strategy, REBOA is associated with improved survival in patients with noncompressible torso hemorrhage.