Antivascular endothelial growth factor in treatment of choroidal osteoma not associated with choroidal neovascular membrane

Abstract

To report the case of a 52-year-old female with recent complaint of decreased vision associated with a well-defined depigmented lesion in the macula in the right eye. She had a history of surgery for pituitary microadenoma and breast lump excision. Based on spectral-domain optical coherence tomography, fundus fluorescein angiography, indocyanine green angiography, and B-scan ultrasonography, a diagnosis of the right eye choroidal osteoma was made. Subretinal fluid (SRF) was noted in the absence of obvious classic choroidal neovascularization (CNV). The patient was given monthly intravitreal ranibizumab injection over 3 months. Visual acuity was 20/80 preinjection, which dramatically improved to 20/20 after the injections without any additional treatment. We report an interesting case where SRF was noted in the absence of evident CNV and that antivascular endothelial growth factor can be considered as an effective option even in the absence of an evident CNV.

Keywords

• Antivascular endothelial growth factor
• choroidal osteoma
• choroidal neovascularization
• ranibizumab
• subretinal fluid