Current therapies in episodic migraine management

Abstract

Migraine is a common neurological disease characterized by severe, recurrent episodes of throbbing, unilateral, headache. Non pharmacologic migraine treatment refers to the patient behavioural modification in order to avoid trigger. Current therapies in migraine attack treatment are non-specific drugs (non-steroidal anti-inflammatory drugs, aspirin, antiemetics) and specific antimigraine drugs (ergot alkaloids, serotonin 5-HT1B/1D receptor agonists – triptans). For migraine prophylaxis are recommended beta-blockers (metoprolol, propranolol), calcium channel blockers (flunarizine), antiepileptic drugs (valproic acid, topiramate), antidepressants (amitriptilyne, fluoxetine).

Keywords

• migraine
• ergot alkaloids
• triptans
• antiepileptic drugs