Hitit Medical Journal (Feb 2024)

Can HCG MoM Ratio Predict Preeclampsia?

  • Yaprak Ustun,
  • Ali Çağlar,
  • Şevki Çelen,
  • Onur Kaya,
  • Sadullah Özkan,
  • Fahri Burçin Fıratlıgil,
  • Erkan Sağlam,
  • Kadriye Yakut Yücel,
  • Levent Dereli,
  • Mehmet Obut,
  • Aykut Kından,
  • Seval Yılmaz Ergani,
  • Gizem Kızılboğa,
  • Betül Tokgöz,
  • Caner Çakır

DOI
https://doi.org/10.52827/hititmedj.1298037
Journal volume & issue
Vol. 6, no. 1
pp. 21 – 27

Abstract

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Objective: To predict preeclampsia by the ratio of the HCG MoM value in the first and second trimester screening tests. Material and Methods: The HCG-MoM values of 136 pregnant women with preeclampsia and 222 normatensive pregnant women used for first and second-trimester screening tests were proportioned , and the difference between the groups was examined. Numeric variables are expressed as mean ± standard deviation, median (minimum – maximum), and categorical variables as n (%). Results: HCG MoM values were not different between the two groups and were within the accepted international values. The ratio of the free HCG MoM value in the first trimester to the intact HCG MoM value in the second trimester was significantly higher in the control group (1.06) than in the study group (0.99) (p=0.02). Conclusion: Rating the MoM values of β-HCG, a biochemical marker used in screening tests for chromosomal anomaly, may predict preeclampsia in the later weeks of pregnancy.

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