Advantages and disadvantages of various bulking agents in endoscopic treatment of vesicoureteral reflux

Abstract

Vesicoureteral reflux is the most common urological disease in children population. The aim of this study was to show advantages and disadvantages of various bulking agents that were used in endoscopic correction of vesicoureteral reflux and to show the results achieved in University children's hospital. In this retrospective study data from 50 patients that were treated in 2 years period were analyzed. Several physicians used Deflux injection. The results of this study were compared with a previous study performed in the same study centre that was marked as the standard one. Cure rate after the first injection was 84,8%, an additional 7,6% ureteral units were downgraded and didn't need further treatment, which gives an overall success rate of 92,4% after a single injection. A second injection raised the cure rate to 96, 2%. Open surgery was performed in only 3 (3.8%) cases. We didn't have complications in the form of ureterovesical junction obstruction. Compared to the standard study we achieved similar success. Deflux injection is safe and effective and endoscopic treatment is definitely a feasible procedure. The only thing that remains is to find the bulking agent that will be more effective and safe.

Keywords

• bulking agents
• reflux
• children