Romanian Journal of Laboratory Medicine (Jan 2023)

The Role of procollagen type 1 amino-terminal propertied (P1NP) Cytochrome P450 (CYPs) and Osteoprotegerin (OPG) as Potential Bone function markers in Prostate Cancer Bone Metastasis

  • Yousif Pshtiwan A.,
  • Ismail Parween Abdulsamad

DOI
https://doi.org/10.2478/rrlm-2023-0006
Journal volume & issue
Vol. 31, no. 1
pp. 25 – 34

Abstract

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Background: Procollagen type I amino-terminal propeptide (PINP) is often present during osteoblast development and could be a biomarker of early bone development. Osteoprotegerin (OPG) may protect tumor cells from apoptosis. Cytochrome P450 enzymes help tumor development and treatment (CYPs). Cytochrome P450 activates and deactivates anticancer drugs and procarcinogens.

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