Chorioamnionitis: a diagnostic approach

Abstract

Introduction: Chorioamnionitis has been defined as inflammation of the amnion and chorion membranes in response to microbial invasion or other pathological process. May be clinical when clinical manifestations of local and systemic inflammation is present, subclinical when no clinical signs; histological if there is microscopic evidence of infection or inflammation in placental examination. The frequency of chorioamnionitis is highly variable, depending on the risk factors of the population studied, the criteria used for diagnosis (clinical or histological) and gestational age. This clinical entity is important because results in maternal, fetal and neonatal aftermath such as postpartum endometritis, pelvic abscess and high risk of caesarean section in the mother. In the fetus, Prematurity, perinatal death, pneumonia, sepsis, intraventricular hemorrhage and cerebral palsy. Make an early and accurate diagnosis is essential to prevent these aftermath. Objective: Carry out a literature review on the diagnosis of chorioamnionitis. Methods: A search of the literature published during the last 5 years in Pubmed, Tripdatabase, Science direct and Embase biomedical was made, selecting the most relevant literature on chorioamnionitis. Conclusions: Despite medical advances in diagnostic methods, unify parameters for early diagnosis of chorioamnionitis is still a challenge, as shown by the variability of the evidence found in this review.

Keywords

• Corioamnionitis, amnionitis, diagnóstico, marcadores biológicos