Nature Communications (Oct 2021)

Structural basis for high selectivity of a rice silicon channel Lsi1

  • Yasunori Saitoh,
  • Namiki Mitani-Ueno,
  • Keisuke Saito,
  • Kengo Matsuki,
  • Sheng Huang,
  • Lingli Yang,
  • Naoki Yamaji,
  • Hiroshi Ishikita,
  • Jian-Ren Shen,
  • Jian Feng Ma,
  • Michihiro Suga

DOI
https://doi.org/10.1038/s41467-021-26535-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 14

Abstract

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The rice Lsi1 aquaporin mediates uptake of silicic acid via the roots. Here the authors show the crystal structure of rice Lsi1 and characterize a unique five residue hydrophilic selectivity filter providing a structural basis for the highly selective activity of Lsi1 in Si uptake.