Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains

Valérie Wattelet-Boyer; Lysiane Brocard; Kristoffer Jonsson; Nicolas Esnay; Jérôme Joubès; Frédéric Domergue; Sébastien Mongrand; Natasha Raikhel; Rishikesh P. Bhalerao; Patrick Moreau; Yohann Boutté

doi:10.1038/ncomms12788

Nature Communications (Sep 2016)

Enrichment of hydroxylated C24- and C26-acyl-chain sphingolipids mediates PIN2 apical sorting at trans-Golgi network subdomains

Valérie Wattelet-Boyer,
Lysiane Brocard,
Kristoffer Jonsson,
Nicolas Esnay,
Jérôme Joubès,
Frédéric Domergue,
Sébastien Mongrand,
Natasha Raikhel,
Rishikesh P. Bhalerao,
Patrick Moreau,
Yohann Boutté

Affiliations

Valérie Wattelet-Boyer: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux
Lysiane Brocard: Bordeaux Imaging Center, UMS 3420 CNRS, US4 INSERM, University of Bordeaux
Kristoffer Jonsson: Department of Forest Genetics and Plant Physiology, Umeå Plant Science Centre, Swedish University for Agricultural Sciences
Nicolas Esnay: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux
Jérôme Joubès: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux
Frédéric Domergue: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux
Sébastien Mongrand: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux
Natasha Raikhel: Department of Botany and Plant Sciences, Center for Plant Cell Biology, University of California
Rishikesh P. Bhalerao: Department of Forest Genetics and Plant Physiology, Umeå Plant Science Centre, Swedish University for Agricultural Sciences
Patrick Moreau: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux
Yohann Boutté: UMR 5200 Membrane Biogenesis Laboratory, CNRS-University of Bordeaux

DOI: https://doi.org/10.1038/ncomms12788
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 15

Abstract

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Sphingolipids in the trans-Golgi network have been implicated in polar trafficking. Here Wattelet-Boyer et al. show that hydroxylated C24- and C26-acyl-chain sphingolipids are enriched in trans-Golgi network subdomains that are critical for polar sorting of the PIN2 auxin carrier in plant cells.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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